Dal 1995 ad oggi l’unico agente trombolitico per il trattamento dell’ictus acuto è stato l’alteplase. Il Tenecteplase è un attivatore del plasminogeno modificato in cui la sostituzione di tre aminoacidi conferisce alla molecola una maggiore specificità e stabilità, per cui è possibile la sua somministrazione in un singolo bolo, evitando così l’infusione di mantenimento di…
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